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Development of membrane-targeting TPP+-chloramphenicol conjugates to combat methicillin-resistant staphylococcus aureus (MRSA) infections 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 264, 页码: 13
作者:  Li, Tao;  He, Xiaoli;  Tao, Wenlan;  Zhang, Ruixue;  He, Qiaolin;  Gong, Hongzhi;  Liu, Ye;  Luo, Dong;  Zhang, Maojie;  Zou, Cheng;  Zhang, Shao-Lin;  He, Yun
收藏  |  浏览/下载:7/0  |  提交时间:2024/02/23
Triphenylphosphonium cation  Membrane disruption  Drug-resistance  
2,4-Diacetylphloroglucinol (DAPG) derivatives rapidly eradicate methicillin-resistant staphylococcus aureus without resistance development by disrupting membrane 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 261, 页码: 18
作者:  Zhong, Yifan;  He, Xiaoli;  Tao, Wenlan;  Feng, Jizhou;  Zhang, Ruixue;  Gong, Hongzhi;  Tang, Ziyi;  Huang, Chao;  He, Yun
收藏  |  浏览/下载:8/0  |  提交时间:2023/12/25
4-Diacetylphloroglucinol  MRSA  Antimicrobial resistance  Cell membrane  Synergy  Biofilm  
Optimization of the Natural Product Calothrixin A to Discover Novel Dual Topoisomerase I and II Inhibitors with Improved Anticancer Activity 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 11, 页码: 8040-8061
作者:  Yang, Xiaohong;  Wang, Zhi-Peng;  Xiang, Sichuan;  Wang, Daoqiang;  Zhao, Yi;  Luo, Dong;  Qiu, Yanfei;  Huang, Chao;  Guo, Jian;  Dai, Yuanwei;  Zhang, Shao-Lin;  He, Yun
收藏  |  浏览/下载:38/0  |  提交时间:2022/08/22
Glutathione-responsive multifunctional nanoparticles based on mannose-modified pillar[5]arene for targeted antibiotic delivery against intracellular methicillin-resistant S. aureus 期刊论文
MATERIALS CHEMISTRY FRONTIERS, 2021, 页码: 8
作者:  Peng, Haibo;  Xie, Beibei;  Cen, Xianfeng;  Dai, Jiaojiao;  Dai, Yuanwei;  Yang, Xiaohong;  He, Yun
收藏  |  浏览/下载:38/0  |  提交时间:2022/08/22