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Studies on Proximate Composition and Phytochemical Profiling of Turbinaria ornata and its Antiproliferative Effect on Y79 Cell Lines
Remya, R. R.1; Rajasree, S. R. Radhika1,2; Suman, T. Y.1,3,4; Aranganathan, L.1; Gayathri, S.1; Gobalakrishnan, M.1; Karthih, M. G.1
2019-10-01
摘要Marine brown algae Turbinaria ornata (T. ornata) that grows along Tamilnadu coast (Gulf of Mannar) were collected to study the composition of major and minor nutrients, phytochemical constituents and to evaluate the cytotoxic effect. Proximate composition of this brown seaweed was investigated by the determination of moisture, ash, protein, lipid and carbohydrate. The mineral content was analyzed using Inductive Coupled Plasma- Mass Spectrometry (ICP-MS). In general, the results of proximate analysis showed that moisture content (83.62%) was most abundant followed by carbohydrate (43.7% dry weight), ash content (23.4%) protein (5.4% dry weight) and lipid (1.9% dry weight). This work presents the data on the mineral content such as manganese, sodium, magnesium, potassium, zinc etc. of the brown algae. The chemical components present in the methanolic extract of the sample were analyzed using Gas Chromatography-Mass Spectrometer (GC-MS). The presence of secondary metabolites illustrate that this brown seaweed T. ornata can be harnessed for their biomedical potentials. Apart from this, the methanolic extract extracted also showed cytotoxic activity against human retinoblastoma Y79 cell lines and the Inhibitory Concentration (IC50) was found to be at 6.37 mu g/mL. Further research should be explored for the beneficial application of T. ornata as a potent therapeutic tool against cancer.
关键词Turbinaria ornata ICP-MS GC-MS Phytochemical screening Cytotoxicity
DOI10.1007/s41208-019-00159-x
发表期刊THALASSAS
ISSN0212-5919
卷号35期号:2页码:495-502
通讯作者Rajasree, S. R. Radhika(radhiin@gmail.com)
收录类别SCI
WOS记录号WOS:000486226000017
语种英语