KMS Chongqing Institute of Green and Intelligent Technology, CAS
| nanoporebasedfourthgenerationdnasequencingtechnology | |
Feng Yanxiao; Zhang Yuechuan; Ying Cuifeng; Wang Deqiang ; Du Chunlei
| |
| 2015 | |
| 摘要 | Nanopore-based sequencers, as the fourth-generation DNA sequencing technology, have the potential to quickly and reliably sequence the entire human genome for less than $1000, and possibly for even less than $100. The single-molecule techniques used by this technology allow us to further study the interaction between DNA and protein, as well as between protein and protein. Nanopore analysis opens a new door to molecular biology investigation at the single-molecule scale. In this article, we have reviewed academic achievements in nanopore technology from the past as well as the latest advances, including both biological and solid-state nanopores, and discussed their recent and potential applications. |
| 发表期刊 | genomicsproteomicsbioinformatics
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| ISSN | 1672-0229 |
| 卷号 | 13期号:1页码:4 |
| 语种 | 英语 |
