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Mixed-solvent liquid exfoliated MoS2NPs as peroxidase mimetics for colorimetric detection of H2O2and glucose
Zhao, Yuehua1,2; Huang, Yu1; Wu, Jiangling3; Zhan, Xiaoli4; Xie, Yuanyang1,2; Tang, Dongyun1; Cao, Haiyan5; Yun, Wen6
2018
摘要Ultra-small molybdenum disulfide nanoparticles (MoS2NPs) were prepared by a facile liquid exfoliation method with ethanol/water as the solvent. The produced MoS2NPs were of high purity due to the easily removable ethanol/water solution. The prepared MoS2NPs exhibited an intrinsic peroxidase-like activity in analogy to that of horseradish peroxidase (HRP). A custom-made spectrometer was employed to investigate the peroxidase-like activity of MoS2NPs in the presence of H2O2and glucose. The change in absorption detected from MoS2NPs is proportional to the amount of target. The calibration curve of H2O2and glucose shows a good relationship between the concentration of target and the change in the absorption of MoS2NPs. The limit of detection of H2O2and glucose achieved by this method could approach 1.25 μM and 7 μM respectively. This method has been applied for the detection of glucose in serum from humans. Therefore, these produced MoS2NPs offer an alternative high-efficiency and economic way to detect diabetes. © The Royal Society of Chemistry 2018.
DOI10.1039/c7ra12584d
发表期刊RSC Advances
卷号8期号:13页码:7252-7259
收录类别EI
语种英语
EISSN20462069