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Displacement chemistry-based nanopore analysis of nucleic acids in complicated matrices
Wang, Liang1; Chen, Xiaohan2; Zhou, Shuo1; Roozbahani, Golbarg M.2; Zhang, Youwen2; Wang, Deqiang1; Guan, Xiyun2
2018-12-25
摘要To overcome the effect of other components of complicated biological samples on nanopore stochastic sensing, displacement chemical reaction was utilized to selectively extract the target nucleic acid from whole blood. Given its simplicity and high sensitivity for detecting nucleic acids, our developed displacement chemistry-based nanopore sensing strategy offers the potential for fieldable/point-of-care diagnostic applications.
DOI10.1039/c8cc07944g
发表期刊CHEMICAL COMMUNICATIONS
ISSN1359-7345
卷号54期号:99页码:13977-13980
收录类别SCI
WOS记录号WOS:000453549800011
语种英语