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	Pollution level and ecological risk assessment of typical pharmaceutically active compounds in the river basins of main districts of Chongqing
	Yan, Qing1; Zi, Cheng-Fang1; Zhang, Yi-Xin1; Gan, Xiu-Mei1; Peng, Xu-Ya1; Gao, Xu1,2; Guo, Jin-Song1,3
	2013
摘要	The pollution characteristics of eight therapeutic groups, including antibiotics, analgesics, antiepileptics, antilipidemics, antihypersensitives, in the Yangtze River, Jialing River and Huaxi stream which is a tributary of the Yangtze River in Chongqing, were investigated using the high-performance liquid chromatography-electrospray ionization tandem mass spectrometry. Results showed that 14 of the 21 target PhACs were detected and the concentration levels ranged from 1.1 to 35.5 ng/L in the Yangtze River and Jialing River, while ranged from 10.3 to 445.6 ng/L in the Huaxi stream. Moxifloxacin, bezafibrate, gemfibrozil, diclofenac and atorvastatin were only detected in the Huaxi stream. The concentrations varied from 0.6-31.4 ng/L. Amlodipine was not found in this study. The flow of Huaxi stream is small and the direct emission of the surrounding sewage was very serious. Consequently, the concentrations of the target PhACs, except for sulfamethazine, carbamazepine and simvastatin, in Huaxi stream were statistically significantly higher than in the other two rivers. Risk quotients, the ratios of measured environmental concentrations (MEC) and the predicted no-effect concentrations, were over than 0.1 for sulfamethoxazole, ofloxacin, erythromycin and clofibric acid, indicating that the environment concentrations of single compounds may have a medium ecological risk, which is closely related to their larger consumption.
发表期刊	Research of Environmental Sciences
ISSN	10016929
卷号	26期号:11页码:1178-1185
通讯作者	Gao, X. (gaoxu@cqu.edu.cn)
收录类别	EI
语种	中文