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The combination of DNA nanostructures and materials for highly sensitive electrochemical detection
Tian, Rong1,2; Ma, Wenhao3; Wang, Lue4; Xie, Wanyi1,2; Wang, Yunjiao1,2; Yin, Yajie1,2; Weng, Ting1,2; He, Shixuan1,2; Fang, Shaoxi1,2; Liang, Liyuan1,2
2024-06-01
摘要Due to the wide range of electrochemical devices available, DNA nanostructures and material -based technologies have been greatly broadened. They have been actively used to create a variety of beautiful nanostructures owing to their unmatched programmability. Currently, a variety of electrochemical devices have been used for rapid sensing of biomolecules and other diagnostic applications. Here, we provide a brief overview of recent advances in DNA -based biomolecular assays. Biosensing platform such as electrochemical biosensor, nanopore biosensor, and field-effect transistor biosensors (FET), which are equipped with aptamer, DNA walker, DNAzyme, DNA origami, and nanomaterials, has been developed for amplification detection. Under the optimal conditions, the proposed biosensor has good amplification detection performance. Further, we discussed the challenges of detection strategies in clinical applications and offered the prospect of this field.
关键词DNA nanostructures Nanopore FET Nanogap Nucleic acids Biosensor
DOI10.1016/j.bioelechem.2024.108651
发表期刊BIOELECTROCHEMISTRY
ISSN1567-5394
卷号157页码:17
通讯作者Tian, Rong(tianrong@cigit.ac.cn) ; Wang, Liang(wangliang83@cigit.ac.cn) ; Wang, Deqiang(dqwang@cigit.ac.cn)
收录类别SCI
WOS记录号WOS:001170975000001
语种en