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Two-photon polymerization microfabrication of hydrogels: an advanced 3D printing technology for tissue engineering and drug delivery
Xing, Jin-Feng1; Zheng, Mei-Ling2,3; Duan, Xuan-Ming2,3,4
2015
Abstract3D printing technology has attracted much attention due to its high potential in scientific and industrial applications. As an outstanding 3D printing technology, two-photon polymerization (TPP) microfabrication has been applied in the fields of micro/nanophotonics, micro-electromechanical systems, microfluidics, biomedical implants and microdevices. In particular, TPP microfabrication is very useful in tissue engineering and drug delivery due to its powerful fabrication capability for precise microstructures with high spatial resolution on both the microscopic and the nanometric scale. The design and fabrication of 3D hydrogels widely used in tissue engineering and drug delivery has been an important research area of TPP microfabrication. The resolution is a key parameter for 3D hydrogels to simulate the native 3D environment in which the cells reside and the drug is controlled to release with optimal temporal and spatial distribution in vitro and in vivo. The resolution of 3D hydrogels largely depends on the efficiency of TPP initiators. In this paper, we will review the widely used photoresists, the development of TPP photoinitiators, the strategies for improving the resolution and the microfabrication of 3D hydrogels.
DOI10.1039/c5cs00278h
Source PublicationCHEMICAL SOCIETY REVIEWS
ISSN0306-0012
Volume44Issue:15Pages:5031-5039
Corresponding AuthorXing, JF (reprint author), Tianjin Univ, Sch Chem Engn & Technol, Tianjin 300072, Peoples R China.
Indexed BySCI
WOS IDWOS:000358219300004
Language英语
Funding ProjectNational Natural Science Foundation of China[31371014] ; National Natural Science Foundation of China[91323301] ; National Natural Science Foundation of China[61205194] ; National Natural Science Foundation of China[61475164] ; Tianjin Natural Science Foundation[13JCYBJC16500]
WOS Research AreaChemistry
WOS SubjectChemistry, Multidisciplinary
PublisherROYAL SOC CHEMISTRY
Citation statistics
Cited Times:316[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://124.16.212.251/handle/2HOD01W0/1802
Collection机器人与3D打印技术创新中心
Corresponding AuthorXing, Jin-Feng
Affiliation1.Tianjin Univ, Sch Chem Engn & Technol, Tianjin 300072, Peoples R China
2.Chinese Acad Sci, Tech Inst Phys & Chem, Lab Organ NanoPhoton, Beijing 100190, Peoples R China
3.Chinese Acad Sci, Tech Inst Phys & Chem, Key Lab Funct Crystals & Laser Technol, Beijing 100190, Peoples R China
4.Chinese Acad Sci, Chongqing Inst Green & Intelligent Technol, Shuitu Technol Dev Zone, Chongqing 400714, Peoples R China
Recommended Citation
GB/T 7714
Xing, Jin-Feng,Zheng, Mei-Ling,Duan, Xuan-Ming. Two-photon polymerization microfabrication of hydrogels: an advanced 3D printing technology for tissue engineering and drug delivery[J]. CHEMICAL SOCIETY REVIEWS,2015,44(15):5031-5039.
APA Xing, Jin-Feng,Zheng, Mei-Ling,&Duan, Xuan-Ming.(2015).Two-photon polymerization microfabrication of hydrogels: an advanced 3D printing technology for tissue engineering and drug delivery.CHEMICAL SOCIETY REVIEWS,44(15),5031-5039.
MLA Xing, Jin-Feng,et al."Two-photon polymerization microfabrication of hydrogels: an advanced 3D printing technology for tissue engineering and drug delivery".CHEMICAL SOCIETY REVIEWS 44.15(2015):5031-5039.
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