中文版 | English
CSpace
Enhanced Electrochemical Sensing of Butylated Hydroxy Anisole through Hollow Metal-Organic Frameworks with Gold Nanoparticles and Enzymes
Sun, Wang1; Chu, Huacong1; Zha, Xiaoqian1; Lu, Shun2; Wang, Yang1
2023-08-09
摘要Reliable methods for detecting butylated hydroxy anisole(BHA)in food and pharmaceutical products are crucial due to its potentialtoxicity. The utilization of hollow zeolite imidazolate framework-8(ZIF-8) as host materials possessing both conducting and enzymaticproperties presents a promising electrochemical sensing material.Herein, a facile synthesis strategy of ternary nanocomposite HRP@HZIF-Auwas proposed, which involves the immobilization of horse radish peroxidase(HRP) into ZIF-8 through a coprecipitation method. Then, a hybridporous HRP@HZIF was etched with tannic acid, which is further functionalizedwith gold nanoparticles (Au NPs). The HRP@HZIF-Au nanomaterial tendsto be spherical with a size of about 550 nm. The resulting HRP@HZIF-Auelectrochemical sensor exhibits a significant electrocatalytic performancefor detecting BHA, which has an extended linear detection range of0.1 to 1600 & mu;mol L-1 and a low detection limitof 0.03 & mu;mol L-1 (S/N = 3). Remarkably, theHRP@HZIF-Au electrochemical sensor demonstrates good interferenceselectivity and storage stability (& SIM;20 days). The remarkablecatalytic efficiency of HRP@HZIF-Au for BHA may be attributed to synergisticeffects arising from hollow ZIF-8, HRP-promoted electron transfer,and Au NPs.
关键词hollow metal organic frameworks enzyme immobilization gold nanoparticles butylated hydroxy anisole electrochemical sensor
DOI10.1021/acsanm.3c02832
发表期刊ACS APPLIED NANO MATERIALS
页码10
通讯作者Lu, Shun(lushun@cigit.ac.cn) ; Wang, Yang(wangyzu@126.com)
收录类别SCI
WOS记录号WOS:001044491000001
语种英语