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Chromatographic paper embedded with silver nanostructure as a disposable substrate for surface-enhanced Raman spectroscopy and catalytic reactor
Nie, Bei1,2; Zhou, Qiuhong1,3; He, Jiming1; Yang, Fumo1
2015-02-01
摘要The high cost of regular diagnostic kits severely impeded its uses for routine clinical assay and fieldworks. A cost-effective chromatography paper is chemically modified with Ag nanostructures using the simple electroless silver deposition, producing a scalable and disposable substrate for surface-enhanced Raman spectroscopy, as well as a large scale of catalytic active sites over many chemical reactions. Synergetic measurement including surface-enhanced Raman spectroscopy and laser desorption ionization-mass spectrometry is performed on Ag decorated filter paper using a thiol containing compound as indicator, allowing for the acquisition of spatially correlated spectroscopy in the tandem mode. In addition, hydrophilic porous cellulose network that contains a certain amount of liquid naturally served as a chemical reactor for molecular transport and reaction. Positive results from catalytic reaction on metallized paper convincingly demonstrated that total microanalysis system on paper (-TASoP), as a compelling alternative would find a wide breadth of applications in developing disposable medical devices and customary laboratory assays. Copyright (c) 2015 John Wiley & Sons, Ltd.
关键词electroless deposition silver nanoparticles chromatographic paper surface-enhanced Raman spectroscopy catalytic reactor
DOI10.1002/jrs.4636
发表期刊JOURNAL OF RAMAN SPECTROSCOPY
ISSN0377-0486
卷号46期号:2页码:211-216
通讯作者Nie, B (reprint author), Chinese Acad Sci, Chongqing Inst Green & Intelligent Technol, Analyt Instrument Div, Chongqing, Peoples R China.
收录类别SCI
WOS记录号WOS:000349891900003
语种英语