KMS Chongqing Institute of Green and Intelligent Technology, CAS
| Antimicrobial Activity and Mechanism of Functionalized Quantum Dots | |
Rajendiran, Keerthiga1; Zhao, Zizhen1; Pei, De-Sheng2  ; Fu, Ailing1
| |
| 2019-10-01 | |
| 摘要 | An essential characteristic of quantum dots (QDs) is their antimicrobial activity. Compared with conventional antibiotics, QDs not only possess photoluminescence properties for imaging and photodynamic therapy but also have high structural stability. To enhance their antimicrobial efficiency, QDs usually are functionalized by polymers, including poly(ethylene glycol), polyethyleneimine, and poly-l-lysine. Also, QDs conjugated with polymers, such as poly(vinylpyrrolidone) and polyvinylidene fluoride, are prepared as antimicrobial membranes. The main antimicrobial mechanisms of QDs are associated with inducing free radicals, disrupting cell walls/membranes, and arresting gene expression. The different mechanisms from traditional antibiotics allow QDs to play antimicrobial roles in multi-drug-resistant bacteria and fungi. Since the toxicity of the QDs on animal cells is relatively low, they have broad application in antimicrobial research as an effective alternative of traditional antibiotics. |
| 关键词 | quantum dots antimicrobial efficiency multi-drug resistance reactive oxygen species (ROS) |
| DOI | 10.3390/polym11101670 |
| 发表期刊 | POLYMERS
 |
| 卷号 | 11期号:10页码:13 |
| 通讯作者 | Pei, De-Sheng(peids@cigit.ac.cn) ; Fu, Ailing(fal@swu.edu.cn) |
| 收录类别 | SCI |
| WOS记录号 | WOS:000495382700139 |
| 语种 | 英语 |
